Graduate School of Medicine / School of Medicine, Faculty of Medicine

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Biological Regulation

Orthopaedic Surgery

The field of orthopedics is involved in the understanding, diagnosis and treatment of the motor organs including bones, joints, muscles, ligaments and nerves within the limbs and body trunk, which are directly connected to the quality of day-to-day life.
At present, the authors are engaged in diagnosis and research based on the themes 1) Understanding the clinical condition of joint diseases, 2) Diagnosis and treatment of osseocartilaginous tumors, 3) Diagnosis and treatment of spinal disorders, 4) Sports injuries during physical development, and 5) Treatment of disease in the motor organs within a super-aging society.

  • Staff
  • Research & education
  • Clinical Activities
  • Citizen Activities
  • Achievement
  • History


Professor Hirotaka Chikuda, M.D., Ph.D.
Associate Professor Takashi Yanagawa, M.D., Ph.D.
Lecturer Yoichi Iizuka, M.D., Ph.D.
Tsuyoshi Tajika, M.D., Ph.D.
Assistants Koichi Okamura, M.D., Ph.D.
Takuro Kuboi
Hitoshi Shitara, M.D., Ph.D.
Tokue Mieda, M.D., Ph.D.
Daisuke Tsunoda, M.D., Ph.D.
Tsuyoshi Sasaki, M.D., Ph.D.
Hiroki Kobayashi

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Research & Education

Research content

Upper limbs: Research into conditions of the shoulder joint and ultrasound diagnosis of carpal tunnel syndrome
Rheumatoid arthritis: Image analysis and blood serum marker analysis in rheumatoid arthritis
Osseocartilaginous tumors: Analysis of the molecular autocrine motility factor (AMF) function related to neoplasm mastitis, investigation of malignant soft tissue tumors accompanying lymph node metastasis
Hip joint: Research related to the efficacy of hip harness equipment, and research into blood biochemistry and bone metabolism in degenerative hip disease
Knee joint: Evaluation of ligament balance in artificial knee joint replacement operations using navigation systems, research into muscle metabolism in the muscles surrounding the knee joint before and after artificial knee joint replacement operations using FDG-PET
Spine: Clinical research into the upper spine, anatomical investigation of the spinal nerve root
Details of education

Business education

Medical Department Education
1) Lectures: Responsible for structured lectures for fourth year students, and clinical condition lectures for sixth year students.
2) Clinical practice: Responsible for clinical practice for fifth year students, as well as elective practice.
3) Training conferences: Host research and training conferences on sports medicine research, etc., providing students with opportunities to present their research

Graduate education
1) Lectures: Responsible for basic practice lectures, in which graduate students are taught basic experimental technique
2) Research: Engaged in experiments along with graduate students in line with themes allocated by teaching staff
3) Presentation meetings: Once or twice a year, host a presentation meeting at which details of research are discussed by the class as a whole

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Clinical Activities

The field of orthopedics is divided into various specialist areas. In this department we are not restricted to general orthopedic conditions, but rather accept specialist outpatient consultations regarding all orthopedic conditions, and aim to provide the highest standards of medical care.
In order to relieve our patients’ pain and functional disabilities, and return them to ordinary life as quickly as possible, we work to ensure mutual understanding between doctors and patients, and implement treatment based on this understanding and agreement.

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Citizenship Activities

Motor organs health checks in Katashina Village
Medical support for high school baseball teams
Medical checks for high school baseball pitchers
Medical checks for youth baseball team members
Team doctor for Thespa Kusatsu (soccer team)
Management of Gunma Rheumatism Network (GRN)

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Yanagisawa S, Ohsawa T, Saito K, Kobayashi T, Yamamoto A, Takagishi K. J Morphological evaluation and diagnosis of medial type osteoarthritis of the knee using ultrasound. J Orthop Sci. 2014 Jan 6.(in press)

Iizuka H, Iizuka Y, Kobayashi R, Nishinome M, Sorimachi Y, Takagishi K.The relationship between an intramedullary high signal intensity and the clinical outcome in atlanto-axial subluxation owing to rheumatoid arthritis.Spine J. 2013 Nov 14.(in press)

Kakuta Y, Iizuka H, Kobayashi R, Iizuka Y, Takahashi T, Mohara J, Takagishi K.Gorham disease of the lumbar spine with an abdominal aortic aneurysm: a case report. Spine J. 2014 Jan 1;14(1):e5-9. Epub 2013 Oct 22.

Tajika T, Kobayashi T, Yamamoto A, Kaneko T, Takagishi K.Diagnostic utility of sonography and correlation between sonographic and clinical findings in patients with carpal tunnel syndrome.J Ultrasound Med. 2013 Nov;32(11):1987-93.

Tajika T, Kobayashi T, Kaneko T, Tsunoda D, Tsunoda K, Sutou T, Yamamoto A, Takagishi K.Epidemiological study for personal risk factors and quality of life related to Dupuytren’s disease in a mountain village of Japan.J Orthop Sci. 2013 Oct 16. (in press)

Shitara H, Shinozaki T, Takagishi K, Honda M, Hanakawa T.Movement and afferent representations in human motor areas: a simultaneous neuroimaging and transcranial magnetic/peripheral nerve-stimulation study.Front Hum Neurosci. 2013 Sep 17;7:554.

Tsunoda D, Iizuka H, Iizuka Y, Nishinome M, Takagishi K.Wrist drop and muscle weakness of the fingers induced by an upper cervical spine anomaly.Eur Spine J. 2013 Sep 23. (in press)

Nishinome M, Iizuka H, Iizuka Y, Takagishi K.An analysis of the anatomic features of the cervical spine using computed tomography to select safer screw insertion techniques. Eur Spine J. 2013 Nov;22(11):2526-31.

Yanagisawa S, Sato N, Ohsawa T, Saito K, Shimizu M, Takagishi K. Influence of the anterior-posterior femoral translation on the range of motion in cruciate-retaining total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc. 2013 Jun 22.

Hatayama K, Terauchi M, Saito K, Higuchi H, Yanagisawa S, Takagishi K.The importance of tibial tunnel placement in anatomic double-bundle anterior cruciate ligament reconstruction. Arthroscopy. 2013 Jun;29(6):1072-8.

Hagiwara K, Shinozaki T, Matsuzaki T, Takata K, Takagishi K Immunolocalization of water channel aquaporins in human knee articular cartilage with intact and early degenerative regions.Med Mol Morphol. 2013 Jun;46(2):104-8.

Takechi Y, Mieda T, Iizuka A, Toya S, Suto N, Takagishi K, Nakazato Y, Nakamura K, Hirai H.Impairment of spinal motor neurons in spinocerebellar ataxia type 1-knock-in mice. Neurosci Lett. 2013 Feb 22;535:67-72.

Iizuka H, Iizuka Y, Kobayashi R, Takechi Y, Nishinome M, Ara T, Sorimachi Y, Nakajima T, Takagishi K.Effect of a reduction of the atlanto-axial angle on the cranio-cervical and subaxial angles following atlanto-axial arthrodesis in rheumatoid arthritis. Eur Spine J. 2013 May;22(5):1137-41.

Tsunoda D, Iizuka Y, Iizuka H, Nishinome M, Kobayashi R, Ara T, Yamamoto A, Takagishi K.Associations between neck and shoulder pain (called katakori in Japanese) and sagittal spinal alignment parameters among the general population. J Orthop Sci. 2013 Mar;18(2):216-9.

Kurosawa K, Tsuchiya I, Takagishi K.Trapezial-metacarpal joint arthritis: radiographic correlation between first metacarpal articular tilt and dorsal subluxation. J Hand Surg Am. 2013 Feb;38(2):302-8.

Kobayashi A, Kobayashi T, Kato K, Higuchi H, Takagishi K Diagnosis of radiographically occult lumbar spondylolysis in young athletes by magnetic resonance imaging. Am J Sports Med. 2013 Jan;41(1):169-76.

Nakajima K, Yanagawa T, Watanabe H, Takagishi K.Hyperthermia reduces migration of osteosarcoma by suppression of autocrine motility factor.Oncol Rep. 2012 Dec;28(6):1953-8.

Shinozaki T, Saito K, Kobayashi T, Yanagawa T, Takagishi K. Tartrate-Resistant Acid Phosphatase 5b is a Useful Serum Marker for Diagnosis and Recurrence Detection of Giant Cell Tumor of Bone.Open Orthop J. 2012;6:392-9.

Ohsawa T, Kimura M, Hagiwara K, Yorifuji H, Takagishi K.Clinical and second-look arthroscopic study comparing 2 tibial landmarks for tunnel insertions during double-bundle ACL reconstruction with a minimum 2-year follow-up. Am J Sports Med. 2012 Nov;40(11):2479-86.

Iizuka H, Iizuka Y, Kobayashi R, Takechi Y, Nishinome M, Ara T, Sorimachi Y, Nakajima T, Takagishi K.Characteristics of idiopathic atlanto-axial subluxation: a comparative radiographic study in patients with an idiopathic etiology and those with rheumatoid arthritis. Eur Spine J. 2013 Jan;22(1):54-9.

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September 1944: Opened Orthopedics class within Gunma University Department of Medicine. Dr. Tsuneo ONEDA appointed as first Professor, and the Orthopedics class was the 16th to open in Japan.
1952: Hosted the second Annual Meeting of the Eastern Japan Clinical Orthopedics Association (now the Eastern Japan Association of Orthopedics and Traumatology)
1973: Hosted the 22nd Annual Meeting of the Eastern Japan Association of Clinical Orthopedics
1976: Dr. Eiichi UDAGAWA appointed as second Professor.
1985: Dr. Shigeo MOHARA promoted to professor of the Medical Junior College (Now School of Health Sciences)
1993: Hosted the 26th Conference of the Eastern Japan Association of Orthopedics and Traumatology
1997: Dr. Kenji TAKAGISHI appointed as third Professor.
1999: Hosted the 38th Annual Meeting of the Eastern Japan Association of Orthopedics and Traumatology
2002: Dr. Kenji SHIRAKURA promoted to Professor of the Department of Rehabilitation, Gunma University Hospital
2002: Hosted the 15th Annual Meeting of the Japanese Society of Cartilage Metabolism
2003: Hosted the 30th Annual Meeting of the Japan Shoulder Society
2005: Dr. Hideomi WATANABE promoted as successor to Shigeo MOHARA in the School of Health Sciences
2008: Hosted the 37th Annual Meeting of the Rheumatic Surgery Research Association
2009: Hosted the 35th Annual Meeting of the Japanese Orthopedic Society for Sports Medicine
2011: Hosted the 26th Annual Research Meeting of the Japanese Orthopedic Association
2012: Hosted the 61st Annual Meeting of the Eastern Japan Association of Orthopedics and Traumatology