代謝機能制御系器官代謝制御学
病態制御内科学(内科学第一)
当教室は内分泌糖尿病、呼吸器アレルギー、消化器肝臓を専門とする総合内科学教室であり、患者さんに信頼される医師、実力の備わった医師を目指しています。そのためには自分の診察する患者さん一人一人を大切にし、優しい医師、考える医師となることが肝要です。この様な臨床医師を育成する為に、当教室ではこの10年以上かけて優れた卒後研修システムを構築して来ました。この卒後研修システムの特徴は「全身内科学と専門医修得」の臨床医学が誰でも実践出来ることです。私達の卒後研修システムを実践し、かつ米国で2?4年留学し、世界の最先端の学問を学んで帰国して来た者も大勢活躍しています。当教室は多様な人材の集まりです。懐の深さが私達の内科学教室の特徴なのです。卒後研修システムによる臨床医学と国際的医学研究の両立が出来る当教室への参加を歓迎します。
| 教 授 | 森 昌朋 | |
|---|---|---|
| 院内臨床教授 | 石塚 全 | |
| 准教授 | ||
| 講 師 | 山田 正信 | |
| 岡田 秀一 | ||
| 部内講師(医学) | 河村 修 | |
| 助 教 | 佐藤 哲郎 | |
| 橋本 貢士 | ||
| 土屋 天文 | ||
| 砂長 則明 | ||
| 柿崎 暁 | ||
| 久田 剛志 | ||
| 山崎 勇一 | ||
| 渋沢 信行 | ||
| 助教(病院) | 小野 昭浩 | |
| 下山 康之 | ||
| 堀口 昇男 | ||
| 高橋 洋樹 | ||
| 光学医療診療部 准教授 | 草野 元康 | |
| 光学医療診療部 助教 | 佐藤 賢 | |
研究:研究対象疾患は内科学の中の(1)内分泌・糖尿病(2)呼吸器・アレルギー(3)消化器・肝臓の3専門分野です。いずれの研究グループにも臨床研究推進能力の優れた海外留学経験を有する指導者が、若手医師の研究指導に直接あたっています。また大学院生も数多く学んでおり、米国留学も活発に行っています。詳細は研究室紹介http://www.showa.gunma-u.ac.jp/~ymoch/lab/index.htmを参照してください。研究内容や海外留学などについて質問したいことがあったならば、責任者にメールでも結構ですので、随時、直接質問して下さい。
教育:医学部学生の教育としては(1) 4年生を対象とした内科診断学実習、(2) 4年生対象の臓器・機能別内科系統講義、(3) 5年生対象の病棟実習、 (4) 6年生対象の病室選択実習、(5) 6年生対象の実践病態学講義です。この他に、卒後研修1年目?2年目の実習生(ローテーター)を受け入れて研修指導を行っています。特に5年生、6年生の病棟実習では学生による評価を行っており、実習内容を毎年改善する様にしています。
当科は内分泌糖尿病、呼吸器アレルギー、消化器、肝臓代謝を専門とする総合内科です。患者さんと病気を共感し、希望を持って共に克服することを基本に据えています。関連病院等で診断や治療で難渋している患者さんが数多く紹介されて来ます。これらの患者さんの信頼に応える様に、最先端の遺伝子手法や最新の内視鏡技術、高度先進医療を駆使して治療にあたっています。詳細は最新医療情報http://www.showa.gunma-u.ac.jp/~ymoch/saisin/index.htmを参照して下さい。外来日は月曜、水曜、金曜の午前中で、他は急患患者のみ受付可能です。
英文原著 2011年
Shimizu Y, Matsuzaki S, Satoh T, Koka M, Yokoyama A, Ohkubo T, Ishii Y, Kamiya T, Fueki M, Mori M, Dobashi K.
In-air microparticle induced X-ray emission analysis of particles in interstitial pneumonia lung tissue obtained by transbronchial biopsy.
J Clin Biochem Nutr. 49: 125-130, 2011.
Ishizuka T, Matsuzaki S, Aoki H, Yatomi M, Kamide Y, Hisada T, Tsuburai T, Dobashi K, Ohshima K, Akiyama K, Mori M.
Prevalence of asthma symptoms based on the european community respiratory health survey questionnaire and FENO in university students: gender differences in symptoms and FENO.
Allergy Asthma Clin Immunol. 7: 15, 2011.
Matsuzaki S, Ishizuka T, Yamada H, Kamide Y, Hisada T, Ichimonji I, Aoki H, Yatomi M, Komachi M, Tsurumaki H, Ono A, Koga Y, Dobashi K, Mogi C, Sato K, Tomura H, Mori M, Okajima F.
Extracellular acidification induces connective tissue growth factor production through proton-sensing receptor OGR1 in human airway smooth muscle cells.
Biochem Biophys Res Commun. 413: 499-503, 2011.
Shimizu Y, Dobashi K, Fueki N, Fueki M, Okada T, Tomioka S, Makino S, Mori M.
Changes of immunomodulatory cytokines associated with omalizumab therapy for severe persistent asthma.
J Biol Regul Homeost Agents. 25: 177-186, 2011.
Sato K, Mori M.
Evolving Molecular Mechanism-Based Strategies for Control of Hepatocellular Carcinoma.
Curr Med Chem. 18: 4375-4378, 2011.
Nohara A, Okada S, Ohshima K, Pessin JE, Mori M.
Cyclin-dependent Kinase-5 Is a Key Molecule in Tumor Necrosis Factor-{alpha}-induced Insulin Resistance.
J Biol Chem. 286: 33457-33465, 2011.
Shimizu Y, Matsuzaki S, Dobashi K, Yanagitani N, Satoh T, Koka M, Yokoyama A, Ohkubo T, Ishii Y, Kamiya T, Mori M.
Elemental analysis of lung tissue particles and intracellular iron content of alveolar macrophages in pulmonary alveolar proteinosis.
Respir Res. 2: 88, 2011.
Kudo T, Okamura S, Zhang Y, Masuo T, Mori M.
Topical application of glycyrrhizin preparation ameliorates experimentally induced colitis in rats.
World J Gastroenterol. 17: 2223-2228, 2011.
Shimizu H, Tsuchiya T, Ohtani K, Shimomura K, Oh-I S, Ariyama Y, Okada S, Kishi M, Mori M.
Glucagon plays an important role in the modification of insulin secretion by leptin.
Islets. 3: 150-154, 2011.
Kakizaki S, Takizawa D, Tojima H, Horiguchi N, Yamazaki Y, Mori M.
Nuclear receptors CAR and PXR; therapeutic targets for cholestatic liver disease.
Front Biosci. 17: 2988-3005, 2011.
Kawamura O, Shimoyama Y, Hosaka H, Kuribayashi S, Maeda M, Nagoshi A, Zai H, Kusano M.
Increase of weakly acidic gas esophagopharyngeal reflux (EPR) and swallowing-induced acidic/weakly acidic EPR in patients with chronic cough responding to proton pump inhibitors.
Neurogastroenterol Motil. 23: 411-419, 2011.
Kusano M, Moki F, Hosaka H, Shimoyama Y, Kawamura O, Nagoshi A, Maeda M, Kuribayashi S, Zai H, Mizuide M, Horikoshi T, Mori M, Akuzawa M.
Gastroptosis is Associated with Less Dyspepsia, Rather than a Cause of Dyspepsia, in Japanese Persons.
Intern Med. 50: 667-671, 2011
Kusano M, Zai H, Shimoyama Y, Hosaka H, Kuribayashi S, Kawamura O, Mori M.
Rapid gastric emptying, rather than delayed gastric emptying, might provoke functional dyspepsia.
J Gastroenterol Hepatol. 26 Suppl 3: 75-78, 2011
Sunaga N, Shames DS, Girard L, Peyton M, Larsen JE, Imai H, Soh J, Sato M,
Yanagitani N, Kaira K, Xie Y, Gazdar AF, Mori M, Minna JD.
Knockdown of oncogenic KRAS in non-small cell lung cancers suppresses tumor growth and sensitizes tumor cells to targeted therapy.
Mol Cancer Ther. 10: 336-46, 2011
Tsuchiya T, Okada S, Shimizu H, Mori M.
Cumulative effects of genetic risk variants on the development of common atherosclerosis.
Expert Rev Cardiovasc Ther. 9: 295-8, 2011.
Ohara S, Kawano T, Kusano M, Kouzu T.
Survey on the prevalence of GERD and FD based on the montreal definition and Rome III criteria among patients presenting with epigastric symptoms in Japan.
J Gastroenterol 46: 603-611, 2011.
Kusano M, Moki F, Hosaka H, et al.
Gastroptosis is associated with less dyspepsia, rather than causing dyspepsia, in Japanese persons.
Internal Medicine 50: 667-671, 2011.
Hongo M, Miwa H, Kusano M, et al.
Effect of rabeprazole treatment on health-related quality of life and symptoms in patients with reflux esophagitis: a prospective multicenter observational study in Japan.
J Gastroenterol 46: 297-304, 2011.
Shimoyama Y, Kusano M, Shimoda Y, Ishihara S, Toyomasu Y, Ohno T, Mochiki E, Sano, Hirato J, Mori M.
Paget’s disease of bone resembling bone metastasis from gastric cancer.
Clinical Journal of Gastroenterology 4: 207-211, 2011.
Kusano M, Kuribayashi S, Kawamura O, Shimoyama Y, Hosaka H, Nagoshi A, Zai H, Mori M.
A review of the management of gastric acid-related diseases: focus on rabeprazole
Clinical Medicine Insights.
Gastroenterology Libertas academica 3: 31-43, 2011.
Kawamura O, Shimoyama Y, Hosaka H, Kuribayashi S, Maeda M, Nagoshi A, Zai H, Kusano M.
Increase of weakly acidic gas esophagopharyngeal reflux (EPR) and swallowing-induced acidic/weakly acidic EPR in patients with chronic cough responding to proton pump inhibitors.
Neurogastroenterology and Motility 23: 411-418, 2011.
Nakajima Y, Yamada M, Taguchi R, Satoh T, Hashimoto K, Ozawa A, Shibusawa N, Okada S, Monden T, Mori M.
Cardiovascular complications of patients with aldosteronism associated with autonomous cortisol secretion.
J Clin Endocrinol Metab. 96: 2512-2518, 2011.
Ishida E, Yamada M, Horiguchi K, Taguchi R, Ozawa A, Shibusawa N, Hashimoto K, Satoh T, Yoshida S, Tanaka Y, Yokota M, Tosaka M, Hirato J, Yamada S, Yoshimoto Y, Mori M.
Attenuated expression of menin and p27 (Kip1) in an aggressive case of multiple endocrine neoplasia type 1 (MEN1) associated with an atypical prolactinoma and a malignant pancreatic endocrine tumor.
Endocr J. 58: 287-296, 2011.
Yoshida M, Hiroi M, Imai T, Kikumori T, Himeno T, Nakamura Y, Sasano H, Yamada M, Murakami Y, Nakamura S, Oiso Y.
A case of ACTH-independent macronodular adrenal hyperplasia associated with multiple endocrine neoplasia type 1.
Endocr J. 58: 269-277, 2011.
Hashimoto K, Matsumoto S, Ishida E, Miura A, Horiguchi K, Ozawa A, Shibusawa N, Satoh T, Yamada M, Yamada S, Mori M.
Liver X receptor-α/β expression ratio is increased in ACTH-secreting pituitary adenomas.
Neurosci Lett. 494: 34-37, 2011.
Kaira K, Oriuchi N, Sunaga N, Ishizuka T, Shimizu K, Yamamoto N.
A systemic review of PET and biology in lung cancer.
Am J Transl Res. 3: 383-91, 2011.
Kaira K, Okumura T, Ohde Y, Takahashi T, Murakami H, Kondo H, Nakajima T, Yamamoto N.
Prognostic significance of thymidylate synthase expression in the adjuvant chemotherapy after resection for pulmonary metastases from colorectal cancer.
Anticancer Res. 31: 2763-71, 2011.
Kaira K, Ohde Y, Endo M, Nakagawa K, Okumura T, Takahashi T, Murakami H, Tsuya A, Nakamura Y, Naito T, Kondo H, Nakajima T, Yamamoto N.
Expression of 4F2hc (CD98) in pulmonary neuroendocrine tumors.
Oncol Rep. 26: 931-7, 2011.
Kaira K, Okumura T, Ohde Y, Takahashi T, Murakami H, Oriuchi N, Endo M, Kondo H, Nakajima T, Yamamoto N.
Correlation between 18F-FDG uptake on PET and molecular biology in metastatic pulmonary tumors.
J Nucl Med. 52: 705-11, 2011.
Kaira K, Ayabe E, Takahashi T, Murakami H, Tsuya A, Nakamura Y, Naito T, Endo M, Takahashi M, Yamamoto N.
Thenar muscle metastasis as recurrence of pulmonary squamous cell carcinoma.
Asia Pac J Clin Oncol. 7: 15-6, 2011.
Kaira K, Serizawa M, Koh Y, Miura S, Kaira R, Abe M, Nakagawa K, Ohde Y, Okumura T, Naito T, Murakami H, Takahashi T, Kondo H, Nakajima T, Endo M, Yamamoto N.
Expression of excision repair cross-complementation group 1, breast cancer susceptibility 1, and β III-tubulin in thymic epithelial tumors.
J Thorac Oncol. 6: 606-13, 2011.
Kaira K, Murakami H, Serizawa M, Koh Y, Abe M, Ohde Y, Takahashi T, Kondo H, Nakajima T, Yamamoto N.
MUC1 expression in thymic epithelial tumors: MUC1 may be useful marker as differential diagnosis between type B3 thymoma and thymic carcinoma.
Virchows Arch. 458: 615-20, 2011.
Kaira K, Endo M, Abe M, Nakagawa K, Ohde Y, Okumura T, Takahashi T, Murakami H, Tsuya A, Nakamura Y, Naito T, Hayashi I, Kondo H, Nakajima T, Yamamoto N.
Biologic correlation of 2-[18F]-fluoro-2-deoxy-D-glucose uptake on positron emission tomography in thymic epithelial tumors.
Lung Cancer. 71: 144-50, 2011.
Kaira K, Murakami H, Miura S, Kaira R, Akamatsu H, Kimura M, Ono A, Tsuya A, Nakamura Y, Naito T, Takahashi T, Endo M, Yamamoto N.
18F-FDG uptake on PET helps predict outcome and response after treatment in unresectable thymic epithelial tumors.
Ann Nucl Med. 25: 247-53, 2011.
Kaira K, Oriuchi N, Takahashi T, Nakagawa K, Ohde Y, Okumura T, Murakami H, Shukuya T, Kenmotsu H, Naito T, Kanai Y, Endo M, Kondo H, Nakajima T, Yamamoto N.
LAT1 expression is closely associated with hypoxic markers and mTOR in resected non-small cell lung cancer.
Am J Transl Res. 3: 466-78, 2011.
Kaira K, Sunaga N, Ishizuka T, Shimizu K, Yamamoto N.
The role of 18F-fluorodeoxyglucose positron emission tomography in thymic epithelial tumors.
Cancer Imaging 11: 1-7, 2011.
Sugano M, Shimizu K, Nakano T, Kakegawa S, Miyamae Y, Kaira K, Araki T, Kamiyoshihara M, Kawashima O, Takeyoshi I.
Correlation between computed tomography findings and epidermal growth factor receptor and KRAS gene mutations in patients with pulmonary adenocarcinoma.
Oncol Rep. 26: 1205-11, 2011.
Araki T, Shimizu K, Nakamura T, Baba M, Kawai Y, Nakamura K, Mitani Y, Obayashi K, Aomori T, Fujita Y, Miyamae Y, Kakegawa S, Kaira K, Lezhava A, Hayashizaki Y, Takeyoshi I, Yamamoto K.
Clinical screening assay for EGFR exon 19 mutations using PNA-clamp smart amplification process version 2 in lung adenocarcinoma.
Oncol Rep. 26: 1213-9, 2011.
Kenmotsu H, Naito T, Kimura M, Ono A, Shukuya T, Nakamura Y, Tsuya A, Kaira K, Murakami H, Takahashi T, Endo M, Yamamoto N.
The risk of cytotoxic chemotherapy-related exacerbation of interstitial lung disease with lung cancer.
J Thorac Oncol. 6: 1242-6, 2011.
Kakegawa S, Shimizu K, Sugano M, Miyamae Y, Kaira K, Araki T, Nakano T, Kamiyoshihara M, Kawashima O, Takeyoshi I.
Clinicopathological features of lung adenocarcinoma with KRAS mutations.
Cancer. 117: 4257-66, 2011.
Miyamae Y, Shimizu K, Hirato J, Araki T, Tanaka K, Ogawa H, Kakegawa S, Sugano M, Nakano T, Mitani Y, Kaira K, Takeyoshi I.
Significance of epidermal growth factor receptor gene mutations in squamous cell lung carcinoma.
Oncol Rep. 25: 921-8, 2011.
Shukuya T, Takahashi T, Kaira R, Ono A, Nakamura Y, Tsuya A, Kenmotsu H, Naito T, Kaira K, Murakami H, Endo M, Takahashi K, Yamamoto N.
Efficacy of gefitinib for non-adenocarcinoma non-small-cell lung cancer patients harboring epidermal growth factor receptor mutations: a pooled analysis of published reports.
Cancer Sci. 102: 1032-7, 2011.
Kusano M, Moki F, Hosaka H, Shimoyama Y, Kawamura O, Nagoshi A, Maeda M, Kuribayashi S, Zai H, Mizuide M, Horikoshi T, Mori M, Akuzawa M.
Gastroptosis is associated with less dyspepsia, rather than a cause of dyspepsia, in Japanese persons.
Intern Med. 50: 667-671, 2011.
Tahara H, Takagi H, Sato K, Shimada Y, Tojima H, Hirokawa T, Ohyama T, Horiuchi K, Naganuma A, Arai H, Kakizaki S, Mori M.
A retrospective cohort study of partial splenic embolization for antiviral therapy in chronic hepatitis C with thrombocytopenia.
J Gastroenterol. May 19, 2011.
Nakajima Y, Yamada M, Taguchi R, Satoh T, Hashimoto K, Ozawa A, Shibusawa N, Okada S, Monden T, Mori M.
Cardiovascular Complications of Patients with Aldosteronism Associated with Autonomous Cortisol Secretion.
J Clin Endocrinol Metab. May 18, 2011.
Kamide Y, Utsugi M, Dobashi K, Ono A, Ishizuka T, Hisada T, Koga Y, Uno K, Hamuro J, Mori M.
Intracellular glutathione redox status in human dendritic cells regulates IL-27 production and T-cell polarization.
Allergy. May 5, 2011.
Sunaga N, Imai H, Shimizu K, Shames DS, Kakegawa S, Girard L, Sato M, Kaira K, Ishizuka T, Gazdar AF, Minna JD, Mori M.
Oncogenic KRAS-induced interleukin-8 overexpression promotes cell growth and migration and contributes to aggressive phenotypes of non-small cell lung cancer.
Int J Cancer. May 4, 2011.
Takizawa D, Kakizaki S, Horiguchi N, Yamazaki Y, Tojima H, Mori M.
Constitutive active/androstane receptor promotes hepatocarcinogenesis in a mouse model of non-alcoholic steatohepatitis.
Carcinogenesis. 32: 576-583, 2011.
Ohyama T, Yamazaki Y, Sato K, Horiguchi N, Ichikawa T, Kakizaki S, Takagi H, Mori M. Transforming growth factor-α attenuates hepatic fibrosis: possible involvement of matrix metalloproteinase-1.
Liver Int. 31: 572-584, 2011.
Ishida E, Yamada M, Horiguchi K, Taguchi R, Ozawa A, Shibusawa N, Hashimoto K, Satoh T, Yoshida S, Tanaka Y, Yokota M, Tosaka M, Hirato J, Yamada S, Yoshimoto Y, Mori M.
Attenuated expression of menin and p27 (Kip1) in an aggressive case of multiple endocrine neoplasia type 1 (MEN1) associated with an atypical prolactinoma and a malignant pancreatic endocrine tumor.
Endocr J. 58: 287-296, 2011.
Kusano M, Zai H, Shimoyama Y, Hosaka H, Kuribayashi S, Kawamura O, Mori M.
Rapid gastric emptying, rather than delayed gastric emptying, might provoke functional dyspepsia.
J Gastroenterol Hepatol. 26: 75-78, 2011.
Hashimoto K, Matsumoto S, Ishida E, Miura A, Horiguchi K, Ozawa A, Shibusawa N, Satoh T, Yamada M, Yamada S, Mori M.
Liver X receptor-α/β expression ratio is increased in ACTH-secreting pituitary adenomas.
Neurosci Lett. 494: 34-37, 2011.
Mizuide M, Kakizaki S, Yoshida S, Mori M.
Gastric ulcer revealed by computed tomography in a patient with tongue cancer after percutaneous gastrostomy.
Case Rep Gastroenterol. 5: 136-138, 2011.
Tsuchiya T, Okada S, Shimizu H, Mori M.
Cumulative effects of genetic risk variants on the development of common atherosclerosis.
Expert Rev Cardiovasc Ther. 9: 295-298, 2011.
Zhang Y, Okamura S, Kudo T, Masuo T, Mori M.
Calcineurin inhibition by polaprezinc in rats with experimentally-induced colitis.
Life Sci. 88: 432-439, 2011.
Shimizu Y, Matsuzaki S, Satoh T, Ohkubo T, Yokoyama A, Ishii Y, Kamiya T, Arakawa K, Shimizu K, Tanaka S, Mori M, Dobashi K.
Influence of tissue particles on Fas expression in idiopathic interstitial pneumonia.
Front Biosci (Elite Ed). 3: 65-73, 2011.
英文原著 2010年
Imai H, Kaira K, Oriuchi N, Shimizu K, Tominaga H, Yanagitani N, Sunaga N, Ishizuka T, Nagamori S, Promchan K, Nakajima T, Yamamoto N, Mori M, Kanai Y.
Inhibition of L-type amino acid transporter 1 has antitumor activity in non-small cell lung cancer.
Anticancer Res. 30: 4819-4828, 2010.
Ando T, Okada S, Niijima Y, Hashimoto K, Shimizu H, Tsuchiya T, Yamada M, Ohshima K, Mori M, Ono K.
Impaired glucose tolerance, but not impaired fasting glucose, is a risk factor for early-stage atherosclerosis.
Diabet Med. 27: 1430-1435, 2010.
Kaira K, Oriuchi N, Yanagitani N, Sunaga N, Ishizuka T, Mori M, Endo K.
Assessment of therapy response in lung cancer with &supl;⁸F-α-methyl tyrosine PET.
AJR Am J Roentgenol. 195: 1204-1211, 2010.
Shimoyama Y, Kusano M, Hirano Y, Kudou T, Morita K, Hosaka H, Kawamura O, Hirato J, Mori M.
Onset of gastric Crohn's disease observed endoscopically.
Gastrointest Endosc. 72: 1060-1061, 2010.
Kaira K, Oriuchi N, Shimizu K, Imai H, Tominaga H, Yanagitani N, Sunaga N, Hisada T, Ishizuka T, Kanai Y, Oyama T, Mori M, Endo K.
Comparison of L-type amino acid transporter 1 expression and L-[3-18F]-α-methyl tyrosine uptake in outcome of non-small cell lung cancer.
Nucl Med Biol. 37: 911-916, 2010.
Suzuki H, Kakizaki S, Horiguchi N, Ichikawa T, Sato K, Takagi H, Mori M.
Clinical characteristics of null responders to Peg-IFNα2b/ribavirin therapy for chronic hepatitis C.
World J Hepatol. 2: 401-405, 2010.
Horiguchi K, Hashimoto K, Hashizume M, Masuo T, Suto M, Okajo J, Handa H, Kaneko Y, Yokoo H, Sasaki A, Okada S, Yamada M, Tsukamoto N, Nojima Y, Nakazato Y, Mori M.
Primary bilateral adrenal diffuse large B-cell lymphoma demonstrating adrenal failure.
Intern Med. 49: 2241-2246, 2010.
Ichimonji I, Tomura H, Mogi C, Sato K, Aoki H, Hisada T, Dobashi K, Ishizuka T, Mori M, Okajima F.
Extracellular acidification stimulates IL-6 production and Ca(2+) mobilization through proton-sensing OGR1 receptors in human airway smooth muscle cells.
Am J Physiol Lung Cell Mol Physiol. 299: L567-L577, 2010.
Kusano M, Kuribayashi S, Hosaka H, Shimoyama Y, Maeda M, Kawamura O, Zai H, Mori M.
Gastrointestinal motility and Kanpo medicine.
Nippon Shokakibyo Gakkai Zasshi. 107: 1592-603, 2010.
Tsuchiya T, Shimizu H, Yamada M, Osaki A, Oh-I S, Ariyama Y, Takahashi H, Okada S, Hashimoto K, Satoh T, Kojima M, Mori M.
Fasting concentrations of nesfatin-1 are negatively correlated with body mass index in non-obese males.
Clin Endocrinol (Oxf). 73: 484-490, 2010.
Iizuka H, Kakizaki S, Sohara N, Onozato Y, Ishihara H, Okamura S, Itoh H, Mori M.
Stricture after endoscopic submucosal dissection for early gastric cancers and adenomas.
Dig Endosc. 22: 282-288, 2010.
Kakizaki S, Toyoda M, Ichikawa T, Sato K, Takagi H, Arai H, Sohara N, Iizuka H, Onozato Y, Mori M.
Clinical characteristics and treatment for patients presenting with bleeding duodenal varices.
Dig Endosc. 22: 275-281, 2010.
Matsuzaki S, Ishizuka T, Hisada T, Aoki H, Komachi M, Ichimonji I, Utsugi M, Ono A, Koga Y, Dobashi K, Kurose H, Tomura H, Mori M, Okajima F.
Lysophosphatidic acid inhibits CC chemokine ligand 5/RANTES production by blocking IRF-1-mediated gene transcription in human bronchial epithelial cells.
J Immunol. 185: 4863-4872, 2010.
Yanagisawa M, Takagi H, Takahashi H, Uehara M, Otsuka T, Yuasa K, Hosonuma K, Mori M.
Familial clustering and genetic background of primary biliary cirrhosis in Japan.
Dig Dis Sci. 55: 2651-2658, 2010.
Takizawa D, Kakizaki S, Horiguchi N, Tojima H, Yamazaki Y, Ichikawa T, Sato K, Mori M.
Histone deacetylase inhibitors induce cytochrome P450 2B by activating nuclear receptor constitutive androstane receptor.
Drug Metab Dispos. 38: 1493-1498, 2010.
Aoki H, Hisada T, Ishizuka T, Utsugi M, Ono A, Koga Y, Sunaga N, Nakakura T, Okajima F, Dobashi K, Mori M.
Protective effect of resolvin E1 on the development of asthmatic airway inflammation.
Biochem Biophys Res Commun. 400: 128-133, 2010.
Utsugi M, Dobashi K, Ono A, Ishizuka T, Hisada T, Koga Y, Shimizu Y, Kawata T, Matsuzaki S, Aoki H, Kamide Y, Mori M.
JNK1 and JNK2 differently regulate IL-12 production in THP-1 macrophage cells.
Cytokine. 51: 127-131, 2010.
Shimoyama Y, Kusano M, Uchiyama Y, Mori M.
Education and Imaging. Gastrointestinal: rectal sarcoidosis due to paralytic ileus resembling adult-onset Hirschsprung disease.
J Gastroenterol Hepatol. 25: 1464, 2010.
Nakajima Y, Yamada M, Horiguchi K, Satoh T, Hashimoto K, Tokuhiro E, Onigata K, Mori M.
Resistance to thyroid hormone due to a novel thyroid hormone receptor mutant in a patient with hypothyroidism secondary to lingual thyroid and functional characterization of the mutant receptor.
Thyroid. 20: 917-926, 2010.
Iwasaki Y, Sunaga N, Tomizawa Y, Imai H, Iijima H, Yanagitani N, Horiguchi K, Yamada M, Mori M.
Epigenetic inactivation of the thyroid hormone receptor beta1 gene at 3p24.2 in lung cancer.
Ann Surg Oncol. 17: 2222-2228, 2010.
Kaira K, Sunaga N, Tomizawa Y, Yanagitani N, Shimizu K, Imai H, Utsugi M, Iwasaki Y, Iijima H, Tsurumaki H, Yoshii A, Fueki N, Hisada T, Ishizuka T, Saito R, Mori M.
A phase II study of amrubicin, a synthetic 9-aminoanthracycline, in patients with previously treated lung cancer.
Lung Cancer. 69: 99-104, 2010.
Yamada M, Horiguchi K, Umezawa R, Hashimoto K, Satoh T, Ozawa A, Shibusawa N, Monden T, Okada S, Shimizu H, Mori M.
Troglitazone, a ligand of peroxisome proliferator-activated receptor-{gamma}, stabilizes NUCB2 (Nesfatin) mRNA by activating the ERK1/2 pathway: isolation and characterization of the human NUCB2 gene.
Endocrinology. 151: 2494-2503, 2010.
Kuribayashi S, Kusano M, Kawamura O, Shimoyama Y, Maeda M, Hisada T, Ishizuka T, Dobashi K, Mori M.
Mechanism of gastroesophageal reflux in patients with obstructive sleep apnea syndrome.
Neurogastroenterol Motil. 22: 611-e172, 2010.
Kaira K, Sunaga N, Yanagitani N, Imai H, Utsugi M, Iwasaki Y, Shimizu K, Iijima H, Tsurumaki H, Tomizawa Y, Hisada T, Ishizuka T, Saito R, Mori M.
Phase 2 study of S-1 plus carboplatin in patients with advanced non-small cell lung cancer.
Lung Cancer. 68: 253-257, 2010.
Shimizu Y, Dobashi K, Endou K, Ono A, Yanagitani N, Utsugi M, Sano T, Ishizuka T, Shimizu K, Tanaka S, Mori M.
Decreased interstitial FOXP3(+) lymphocytes in usual interstitial pneumonia with discrepancy of CXCL12/CXCR4 axis.
Int J Immunopathol Pharmacol. 23: 449-461, 2010.
Hashimoto K, Ishida E, Miura A, Ozawa A, Shibusawa N, Satoh T, Okada S, Yamada M, Mori M.
A liver X receptor (LXR)-beta alternative splicing variant (LXRBSV) is preferentially expressed in the pituitary.
Biochem Biophys Res Commun. 394: 548-552, 2010.
Negishi M, Shimomura K, Proks P, Akuzawa M, Takahashi M, Mori M, Shimomura Y, Kobayashi I.
An obese patient with slowly progressive type 1 diabetes diagnosed by ketoacidosis.
Intern Med. 49: 393-395, 2010.
Yanagitani N, Shimizu Y, Kazama T, Dobashi K, Ishizuka T, Mori M.
Eosinophilic bronchiolitis indicating eosinophilic airway disease with overexpression of carcinoembryonic antigen in sinus and bronchiole: case report.
J Biol Regul Homeost Agents. 24: 99-102, 2010.
Imai H, Sunaga N, Shimizu Y, Kakegawa S, Shimizu K, Sano T, Ishizuka T, Oyama T, Saito R, Minna JD, Mori M.
Clinicopathological and therapeutic significance of CXCL12 expression in lung cancer.
Int J Immunopathol Pharmacol. 23: 153-164, 2010.
Matsuzaki S, Shimizu Y, Dobashi K, Nagamine T, Satoh T, Ohkubo T, Yokoyama A, Ishii Y, Kamiya T, Arakawa K, Makino S, Utsugi M, Ishizuka T, Tanaka S, Shimizu K, Mori M.
Analysis on the co-localization of asbestos bodies and Fas or CD163 expression in asbestos lung tissue by in-air micro-pixe.
Int J Immunopathol Pharmacol. 23: 1-11, 2010.
Kusano M, Zai H, Hosaka H, Shimoyama Y, Nagoshi A, Maeda M, Kawamura O, Mori M.
New frontiers in gut nutrient sensor research: monosodium L-glutamate added to a high-energy, high-protein liquid diet promotes gastric emptying: a possible therapy for patients with functional dyspepsia.
J Pharmacol Sci. 112: 33-36, 2010.
Tuboi M, Tsuchiya T, Taguchi R, Tanaka Y, Iwasaki Y, Hashimoto K, Kakizaki S, Okada S, Shimizu H, Mori M.
Insulin allergy whose local/systemic reactions were reduced by desensitization with long-acting insulin analog, glargine.
Nippon Naika Gakkai Zasshi. 99: 133-135, 2010.
Sato K, Mori M.
Current and novel therapies for hepatitis B virus infection.
Mini Rev Med Chem. 10: 20-31, 2010.
英文原著 2009年
Yanagitani N, Kotake M, Ishizuka T, Iwasaki Y, Sunaga N, Mori M.
A case of neurosarcoidosis discovered in a patient complaining of chest pain.
Nihon Kokyuki Gakkai Zasshi. 47: 1087-1092, 2009.
Hashimoto K, Ishida E, Matsumoto S, Shibusawa N, Okada S, Monden T, Satoh T, Yamada M, Mori M.
A liver X receptor (LXR)-beta alternative splicing variant (LXRBSV) acts as an RNA co-activator of LXR-beta.
Biochem Biophys Res Commun. 390: 1260-1265, 2009.
Kaira K, Oriuchi N, Imai H, Shimizu K, Yanagitani N, Sunaga N, Hisada T, Kawashima O, Kamide Y, Ishizuka T, Kanai Y, Nakajima T, Mori M.
CD98 expression is associated with poor prognosis in resected non-small-cell lung cancer with lymph node metastases.
Ann Surg Oncol. 16: 3473-3481, 2009.
Ichikawa T, Takagi H, Mori M.
Abdominal tuberculosis in the absence of pulmonary involvement shown by 2-[fluorine 18] fluoro-2-deoxy-D-glucose positron emission tomography.
Clin Gastroenterol Hepatol. 7: A20, 2009.
Hashizume H, Sato K, Takagi H, Kanda D, Kashihara T, Kiso S, Mori M.
Werner syndrome as a possible cause of non-alcoholic steatohepatitis.
J Clin Pathol. 62: 1043-1045, 2009.
Kaira K, Oriuchi N, Shimizu K, Tominaga H, Yanagitani N, Sunaga N, Ishizuka T, Kanai Y, Mori M, Endo K.
18F-FMT uptake seen within primary cancer on PET helps predict outcome of non-small cell lung cancer.
J Nucl Med. 50: 1770-1776, 2009.
Suzuki H, Toyoda M, Horiguchi N, Kakizaki S, Ohyama T, Takizawa D, Ichikawa T, Sato K, Takagi H, Mori M.
Hepatocyte growth factor protects against Fas-mediated liver apoptosis in transgenic mice.
Liver Int. 29:1562-1568, 2009.
Satoh T, Yoshino S, Katano A, Ishizuka T, Tomaru T, Shibusawa N, Hashimoto K, Yamada M, Mori M.
Isolation of a novel leptin receptor gene promoter preferentially functioning in neuronal cells.
Biochem Biophys Res Commun. 389: 673-677, 2009.
Masuo T, Okamura S, Zhang Y, Mori M.
Cyclosporine A inhibits colorectal cancer proliferation probably by regulating expression levels of c-Myc, p21(WAF1/CIP1) and proliferating cell nuclear antigen.
Cancer Lett. 285: 66-72, 2009.
Kakizaki S, Takizawa D, Tojima H, Yamazaki Y, Mori M.
Xenobiotic-sensing nuclear receptors CAR and PXR as drug targets in cholestatic liver disease.
Curr Drug Targets. 10: 1156-1163, 2009.
Iizuka H, Okamura S, Onozato Y, Ishihara H, Kakizaki S, Mori M.
Endoscopic submucosal dissection for colorectal tumors.
Gastroenterol Clin Biol. 33: 1004-1011, 2009.
Kakizaki S, Suzuki H, Ichikawa T, Sato K, Takagi H, Mori M, Yuasa K.
A case of autoimmune hepatitis which worsened after switching from a brand name to a generic version of prednisolone.
Nippon Shokakibyo Gakkai Zasshi. 106: 1488-1493, 2009.
Kaira K, Oriuchi N, Imai H, Shimizu K, Yanagitani N, Sunaga N, Hisada T, Ishizuka T, Kanai Y, Nakajima T, Mori M.
Prognostic significance of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in stage I pulmonary adenocarcinoma.
Lung Cancer. 66: 120-126, 2009.
Hachisu Y, Okamura S, Tanaka H, Tanaka Y, Morita K, Kudo T, Iida T, Kawamura O, Kusano M, Mori M.
Crohn's disease complicating psoas abscess treated by drainage and infliximab administration.
Nippon Shokakibyo Gakkai Zasshi. 106: 1364-1369, 2009.
Shimizu Y, Dobashi K, Nagoshi A, Kawamura O, Mori M.
Assessment of airway inflammation by exhaled breath condensate and impedance due to gastroesophageal reflux disease (GERD).
Inflamm Allergy Drug Targets. 8: 292-296, 2009.
Satoh T, Ishizuka T, Yoshino S, Tomaru T, Nakajima Y, Shibusawa N, Hashimoto K, Yamada M, Mori M.
Roles of proteasomal 19S regulatory particles in promoter loading of thyroid hormone receptor.
Biochem Biophys Res Commun. 386: 697-702, 2009.
Kaira K, Sunaga N, Yanagitani N, Kawata T, Utsugi M, Shimizu K, Ebara T, Kawamura H, Nonaka T, Ishikawa H, Sakurai H, Suga T, Hara K, Hisada T, Ishizuka T, Nakano T, Mori M.
Phase I study of oral S-1 plus Cisplatin with concurrent radiotherapy for locally advanced non-small-cell lung cancer.
Int J Radiat Oncol Biol Phys. 75: 109-114, 2009.
Shimizu H, Oh-I S, Okada S, Mori M.
Nesfatin-1: an overview and future clinical application.
Endocr J. 56: 537-543, 2009.
Umezawa R, Yamada M, Horiguchi K, Ishii S, Hashimoto K, Okada S, Satoh T, Mori M.
Aberrant histone modifications at the thyrotropin-releasing hormone gene in resistance to thyroid hormone: analysis of F455S mutant thyroid hormone receptor.
Endocrinology. 150: 3425-3432, 2009.
Hashimoto K, Ishida E, Matsumoto S, Okada S, Yamada M, Satoh T, Monden T, Mori M.
Carbohydrate response element binding protein gene expression is positively regulated by thyroid hormone.
Endocrinology. 150: 3417-3424, 2009.
Satoh T, Ishizuka T, Tomaru T, Yoshino S, Nakajima Y, Hashimoto K, Shibusawa N, Monden T, Yamada M, Mori M.
Tat-binding protein-1 (TBP-1), an ATPase of 19S regulatory particles of the 26S proteasome, enhances androgen receptor function in cooperation with TBP-1-interacting protein/Hop2.
Endocrinology. 150: 3283-3290, 2009.
Imai H, Kaira K, Oriuchi N, Yanagitani N, Sunaga N, Ishizuka T, Kanai Y, Endou H, Nakajima T, Mori M.
L-type amino acid transporter 1 expression is a prognostic marker in patients with surgically resected stage I non-small cell lung cancer.
Histopathology. 54: 804-813, 2009.
Kaira K, Oriuchi N, Imai H, Shimizu K, Yanagitani N, Sunaga N, Hisada T, Ishizuka T, Kanai Y, Endou H, Nakajima T, Mori M.
L-type amino acid transporter 1 (LAT1) is frequently expressed in thymic carcinomas but is absent in thymomas.
J Surg Oncol. 99: 433-438, 2009.
Shimizu H, Ohsaki A, Oh-I S, Okada S, Mori M.
A new anorexigenic protein, nesfatin-1.
Peptides. 30: 995-998, 2009.
Yanagitani N, Kaira K, Ishizuka T, Aoki H, Utsugi M, Shimizu Y, Sunaga N, Endou K, Hisada T, Mori M.
Multiple lung metastases presenting as ground-glass opacities in a pulmonary adenocarcinoma: a case report.
Cases J. 2: 6910, 2009.
Hisada T, Ishizuka T, Aoki H, Mori M.
Resolvin E1 as a novel agent for the treatment of asthma.
Expert Opin Ther Targets. 13: 513-522, 2009.
Utsugi M, Dobashi K, Ono A, Ishizuka T, Matsuzaki S, Hisada T, Shimizu Y, Kawata T, Aoki H, Kamide Y, Mori M.
PI3K p110beta positively regulates lipopolysaccharide-induced IL-12 production in human macrophages and dendritic cells and JNK1 plays a novel role.
J Immunol. 182: 5225-5231, 2009.
Kanda D, Takagi H, Kawahara Y, Yata Y, Takakusagi T, Hatanaka T, Yoshinaga T, Iesaki K, Kashiwabara K, Higuchi T, Mori M, Hirota T, Higuchi S, Ieiri I.
Novel large-scale deletion (whole exon 7) in the ABCC2 gene in a patient with the Dubin-Johnson syndrome.
Drug Metab Pharmacokinet. 24: 464-468, 2009.
Kaira K, Oriuchi N, Shimizu K, Ishikita T, Higuchi T, Imai H, Yanagitani N, Sunaga N, Hisada T, Ishizuka T, Kanai Y, Endou H, Nakajima T, Endo K, Mori M.
Correlation of angiogenesis with 18F-FMT and 18F-FDG uptake in non-small cell lung cancer.
Cancer Sci. 100: 753-758, 2009.
Yanagitani N, Ishizuka T, Hironaka M, Kaira K, Imai H, Kawata T, Utsugi M, Shimizu Y, Sunaga N, Hisada T, Mori M.
A case of cryptogenic organizing pneumonia with eosinophilic infiltration which was difficult to distinguish from nonspecific interstitial pneumonia.
Nihon Kokyuki Gakkai Zasshi. 47: 286-290, 2009.
Shimizu Y, Sunaga N, Dobashi K, Fueki M, Fueki N, Makino S, Mori M.
Serum markers in interstitial pneumonia with and without Pneumocystis jirovecii colonization: a prospective study.
BMC Infect Dis. 9: 47, 2009.
Horiguchi K, Yamada M, Satoh T, Hashimoto K, Hirato J, Tosaka M, Yamada S, Mori M.
Transcriptional activation of the mixed lineage leukemia-p27Kip1 pathway by a somatostatin analogue.
Clin Cancer Res. 15: 2620-2629, 2009.
Imai H, Sunaga N, Kaira K, Kawashima O, Yanagitani N, Sato K, Tomizawa Y, Hisada T, Ishizuka T, Hirato J, Saito R, Nakajima T, Mori M.
Clinicopathological features of patients with bronchial-associated lymphoid tissue lymphoma.
Intern Med. 48: 301-306, 2009.
Kaira K, Oriuchi N, Shimizu K, Ishikita T, Higuchi T, Imai H, Yanagitani N, Sunaga N, Hisada T, Ishizuka T, Kanai Y, Endou H, Nakajima T, Endo K, Mori M.
Evaluation of thoracic tumors with (18)F-FMT and (18)F-FDG PET-CT: a clinicopathological study.
Int J Cancer. 124: 1152-1160, 2009.
Shimizu H, Oh-I S, Hashimoto K, Nakata M, Yamamoto S, Yoshida N, Eguchi H, Kato I, Inoue K, Satoh T, Okada S, Yamada M, Yada T, Mori M.
Peripheral administration of nesfatin-1 reduces food intake in mice: the leptin-independent mechanism.
Endocrinology. 150: 662-671, 2009.
Kaira K, Oriuchi N, Imai H, Shimizu K, Yanagitani N, Sunaga N, Hisada T, Ishizuka T, Kanai Y, Endou H, Nakajima T, Mori M.
Prognostic significance of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in early stage squamous cell carcinoma of the lung.
Cancer Sci. 100: 248-254, 2009.
Tsuchiya T, Mori M.
An overview of diseases inducing secondary obesity.
Nippon Rinsho. 67: 357-361, 2009.
Kaira K, Yanagitani N, Sunaga N, Imai H, Utsugi M, Kawata T, Hisada T, Shimizu K, Ishizuka T, Mori M.
Effective gemcitabine plus S-1 treatment in elderly non-small cell lung cancer patients with multiple bone metastases.
Gan To Kagaku Ryoho. 36: 299-300, 2009.
Kaira K, Ishizuka T, Yanagitani N, Sunaga N, Hisada T, Mori M.
Pulmonary traumatic pneumatocele and hematoma.
Jpn J Radiol. 27: 100-102, 2009.
Shimizu Y, Dobashi K, Imai H, Sunaga N, Ono A, Sano T, Hikino T, Shimizu K, Tanaka S, Ishizuka T, Utsugi M, Mori M.
CXCR4+FOXP3+CD25+ lymphocytes accumulate in CXCL12-expressing malignant pleural mesothelioma.
Int J Immunopathol Pharmacol. 22: 43-51, 2009.
Kaira K, Ishizuka T, Yanagitani N, Sunaga N, Tsuchiya T, Hisada T, Mori M.
Forearm muscle metastasis as an initial clinical manifestation of lung cancer.
South Med J. 102: 79-81, 2009.
Zai H, Kusano M, Hosaka H, Shimoyama Y, Nagoshi A, Maeda M, Kawamura O, Mori M.
Monosodium L-glutamate added to a high-energy, high-protein liquid diet promotes gastric emptying.
Am J Clin Nutr. 89: 431-435, 2009.
Hisanaga E, Nagasawa M, Ueki K, Kulkarni RN, Mori M, Kojima I.
Regulation of calcium-permeable TRPV2 channel by insulin in pancreatic beta-cells.
Diabetes. 58: 174-184, 2009.
Negishi M, Shimomura K, Proks P, Mori M, Shimomura Y.
Mechanism of disopyramide-induced hypoglycaemia in a patient with Type 2 diabetes.
Diabet Med. 26: 76-78, 2009.
Matsumoto S, Hashimoto K, Yamada M, Satoh T, Hirato J, Mori M.
Liver X receptor-alpha regulates proopiomelanocortin (POMC) gene transcription in the pituitary.
Mol Endocrinol. 23: 47-60, 2009.
Ono A, Utsugi M, Masubuchi K, Ishizuka T, Kawata T, Shimizu Y, Hisada T, Hamuro J, Mori M, Dobashi K.
Glutathione redox regulates TGF-beta-induced fibrogenic effects through Smad3 activation.
FEBS Lett. 583: 357-362, 2009.
英文原著 2008年
Tahara H, Hirokawa T, Oyama T, Naganuma A, Maruta S, Ban S, Yoshida K, Takagi H, Mori M.
Gastric yolk sac tumor complicated with beta-human chorionic gonadotropin-producing metastases.
Intern Med. 47: 2145-2149, 2008.
Kaira K, Oriuchi N, Imai H, Shimizu K, Yanagitani N, Sunaga N, Hisada T, Tanaka S, Ishizuka T, Kanai Y, Endou H, Nakajima T, Mori M.
l-type amino acid transporter 1 and CD98 expression in primary and metastatic sites of human neoplasms.
Cancer Sci. 99: 2380-2386, 2008.
Ariyama Y, Tanaka Y, Shimizu H, Shimomura K, Okada S, Saito T, Yamada E, Oyadomari S, Mori M, Mori M.
The role of CHOP messenger RNA expression in the link between oxidative stress and apoptosis.
Metabolism. 57: 1625-1635, 2008.
Kaira K, Ishizuka T, Yanagitani N, Sunaga N, Hisada T, Mori M.
Laryngeal sarcoidosis detected by FDG positron emission tomography.
Clin Nucl Med. 33: 878-879, 2008.
Ichikawa T, Sato H, Kaira K, Oh-I S, Kakizaki S, Sato K, Takagi H, Mori M.
Prolonged intrahepatic cholestasis after exposure to loxoprofen.
Clin Ther. 30: 2402-2406, 2008.
Okada S, Yamada E, Saito T, Ohshima K, Hashimoto K, Yamada M, Uehara Y, Tsuchiya T, Shimizu H, Tatei K, Izumi T, Yamauchi K, Hisanaga S, Pessin JE, Mori M.
CDK5-dependent phosphorylation of the Rho family GTPase TC10(alpha) regulates insulin-stimulated GLUT4 translocation.
J Biol Chem. 283: 35455-35463, 2008.
Yamada M, Mori M.
Mechanisms related to the pathophysiology and management of central hypothyroidism.
Nat Clin Pract Endocrinol Metab. 4: 683-694, 2008.
Ishizuka T, Hisada T, Aoki H, Mori M.
Resolvin E1: a novel lipid mediator in the resolution of allergic airway inflammation.
Expert Rev Clin Immunol. 4: 669-672, 2008.
Onozato Y, Kakizaki S, Ishihara H, Sohara N, Iizuka H, Okamura S, Mori M, Ogawa T, Itoh H.
Magnifying endoscopic findings of early duodenal adenocarcinoma in relation to the pathological findings.
Endoscopy. 40 Suppl 2: E92-E93, 2008.
Yanagitani N, Shimizu Y, Kaira K, Tatsuno S, Sunaga N, Ishizuka T, Mori M.
Pulmonary toxicity associated with vinorelbine-based chemotherapy in breast cancer.
Gan To Kagaku Ryoho. 35: 1619-1621, 2008.
Kaira K, Sunaga N, Yanagitani N, Imai H, Utsugi M, Shimizu Y, Kawata T, Hisada T, Shimizu K, Tsuchiya T, Ishizuka T, Mori M.
A case of elderly non-small cell lung cancer effectively treated by combined chemotherapy of gemcitabine and S-1.
Gan To Kagaku Ryoho. 35: 1587-1589, 2008.
Kaira K, Ishizuka T, Tanaka H, Tanaka Y, Yanagitani N, Sunaga N, Hisada T, Ishizuka T, Mori M.
Lung cancer producing granulocyte colony-stimulating factor and rapid spreading to peritoneal cavity.
J Thorac Oncol. 3: 1054-1055, 2008.
Shimizu H, Uehara Y, Okada S, Mori M.
Contribution of fasting and postprandial hyperglycemia to hemoglobin A1c in insulin-treated Japanese diabetic patients.
Endocr J. 55: 753-756, 2008.
Hosoya T, Monden T, Fukabori Y, Hashimoto K, Satoh T, Kasai K, Yamada M, Mori M.
A novel splice variant of the nuclear coactivator p120 functions strongly for androgen receptor: characteristic expression in prostate disease.
Endocr J. 55: 657-665, 2008.
Kaira K, Oriuchi N, Imai H, Shimizu K, Yanagitani N, Sunaga N, Hisada T, Kawashima O, Iijima H, Ishizuka T, Kanai Y, Endou H, Nakajima T, Mori M.
Expression of L-type amino acid transporter 1 (LAT1) in neuroendocrine tumors of the lung.
Pathol Res Pract. 204: 553-561, 2008.
Shimizu Y, Dobashi K, Kusakbe T, Nagamine T, Oikawa M, Satoh T, Haga J, Ishii Y, Ohkubo T, Kamiya T, Arakawa K, Sano T, Tanaka S, Shimizu K, Matsuzaki S, Utsugi M, Mori M.
In-air micro-particle induced X-ray emission analysis of asbestos and metals in lung tissue.
Int J Immunopathol Pharmacol. 21: 567-576, 2008.
Hisanaga E, Park KY, Yamada S, Hashimoto H, Takeuchi T, Mori M, Seno M, Umezawa K, Takei I, Kojima I.
A simple method to induce differentiation of murine bone marrow mesenchymal cells to insulin-producing cells using conophylline and betacellulin-delta4.
Endocr J. 55: 535-543, 2008.
Yanagitani N, Kaira K, Ishizuka T, Aoki H, Kawata T, Utsugi M, Shimizu Y, Sunaga N, Hisada T, Mori M.
A case of large cell neuroendocrine carcinoma in a patient with sarcoidosis.
Nihon Kokyuki Gakkai Zasshi. 46: 574-577, 2008.
Sato K, Takagi H, Ichikawa T, Kakizaki S, Mori M.
Emerging therapeutic strategies for hepatitis C virus infection.
Curr Mol Pharmacol. 1: 130-150, 2008.
Shimizu Y, Dobashi K, Yoshikawa Y, Yabe S, Higuchi S, Koike Y, Mita Y, Utsugi M, Endou K, Takahashi K, Watanabe S, Saito R, Mori M.
Five-antituberculosis Drug-resistance Genes Detection Using Array System.
J Clin Biochem Nutr. 42: 228-234, 2008.
Kaira K, Ishizuka T, Tanaka H, Tanaka Y, Ishizuka T, Yanagitani N, Sunaga N, Hisada T, Mori M.
B-cell non-Hodgkin lymphoma presenting as an endobronchial polypoid mass.
J Thorac Oncol. 3: 530-531, 2008.
Kusano M, Hashizume K, Ehara Y, Shimoyama Y, Kawamura O, Mori M.
Size of hiatus hernia correlates with severity of kyphosis, not with obesity, in elderly Japanese women.
J Clin Gastroenterol. 42: 345-350, 2008.
Kaira K, Ishizuka T, Sunaga N, Hashimoto K, Yanagitani N, Nonaka T, Ebara T, Hisada T, Mori M.
Primary mediastinal synovial sarcoma: a report of 2 cases.
J Comput Assist Tomogr. 32: 238-241, 2008.
Kaira K, Sunaga N, Yanagitani N, Aoki H, Kawata T, Utsugi M, Shimizu Y, Shimizu K, Hisada T, Ishizuka T, Mori M.
Phase I trial of oral S-1 plus gemcitabine in elderly patients with nonsmall cell lung cancer.
Anticancer Drugs. 19: 289-294, 2008.
Aoki H, Hisada T, Ishizuka T, Utsugi M, Kawata T, Shimizu Y, Okajima F, Dobashi K, Mori M.
Resolvin E1 dampens airway inflammation and hyperresponsiveness in a murine model of asthma.
Biochem Biophys Res Commun. 367: 509-515, 2008.
Hosonuma K, Sato K, Honma M, Kashiwabara K, Takahashi H, Takagi H, Mori M.
Small-cell carcinoma of the extrahepatic bile duct: a case report and review of the literature.
Hepatol Int. 2: 129-132, 2008.
Sunaga N, Oriuchi N, Kaira K, Yanagitani N, Tomizawa Y, Hisada T, Ishizuka T, Endo K, Mori M.
Usefulness of FDG-PET for early prediction of the response to gefitinib in non-small cell lung cancer.
Lung Cancer. 59: 203-210, 2008.
Yamazaki Y, Kakizaki S, Takizawa D, Ichikawa T, Sato K, Takagi H, Mori M.
Interstrain differences in susceptibility to non-alcoholic steatohepatitis.
J Gastroenterol Hepatol. 23: 276-282, 2008.
Kosone T, Takagi H, Horiguchi N, Kakizaki S, Sato K, Watanabe Y, Mori M.
Transforming growth factor-alpha accelerates hepatocyte repopulation after hepatocyte transplantation.
J Gastroenterol Hepatol. 23: 260-266, 2008.
Kaira K, Oriuchi N, Imai H, Shimizu K, Yanagitani N, Sunaga N, Hisada T, Tanaka S, Ishizuka T, Kanai Y, Endou H, Nakajima T, Mori M.
Prognostic significance of L-type amino acid transporter 1 expression in resectable stage I-III nonsmall cell lung cancer.
Br J Cancer. 98: 742-748, 2008.
Takakusaki S, Kudo T, Suzuki K, Utsugi M, Tsuchiya T, Shibusawa N, Shimoyama Y, Hisada T, Kawamura O, Kusano M, Mori M.
Intestinal pseudo-obstruction associated with polymyositis successfully treated with somatostatin analog.
Nippon Naika Gakkai Zasshi. 97: 398-400, 2008.
Hagiwara S, Otsuka T, Yamazaki Y, Kosone T, Sohara N, Ichikawa T, Sato K, Kakizaki S, Takagi H, Mori M.
Overexpression of NK2 promotes liver fibrosis in carbon tetrachloride-induced chronic liver injury.
Liver Int. 28: 126-131, 2008.
Kakizaki S, Sohara N, Yamazaki Y, Horiguchi N, Kanda D, Kabeya K, Katakai K, Sato K, Takagi H, Mori M.
Elevated plasma resistin concentrations in patients with liver cirrhosis.
J Gastroenterol Hepatol. 23: 73-77, 2008.
Teshigawara K, Kakizaki S, Horiya M, Kikuchi Y, Hashida T, Tomizawa Y, Sohara N, Sato K, Takagi H, Matsuzaki S, Mori M.
Primary Sjogren's syndrome complicated by bilateral pleural effusion.
Respirology. 13: 155-158, 2008.
Umahara M, Okada S, Yamada E, Saito T, Ohshima K, Hashimoto K, Yamada M, Shimizu H, Pessin JE, Mori M.
Tyrosine phosphorylation of Munc18c regulates platelet-derived growth factor-stimulated glucose transporter 4 translocation in 3T3L1 adipocytes.
Endocrinology. 149: 40-49, 2008.
Kakizaki S, Takizawa D, Yamazaki Y, Nakajima Y, Ichikawa T, Sato K, Takagi H, Mori M, Kasama K.
Nonalcoholic fatty liver disease in Japanese patients with severe obesity who received laparoscopic Roux-en-Y gastric bypass surgery (LRYGB) in comparison to non-Japanese patients.
J Gastroenterol. 43: 86-92, 2008.
Zhao JJ, Shimizu Y, Dobashi K, Kawata T, Ono A, Yanagitani N, Kaira K, Utsugi M, Hisada T, Ishizuka T, Mori M.
The relationship between oxidative stress and acid stress in adult patients with mild asthma.
J Investig Allergol Clin Immunol. 18: 41-45, 2008.
英文原著 2007年
Onozato Y, Kakizaki S, Iizuka H, Mori K, Takizawa D, Ohyama T, Arakawa K, Arai H, Ishihara H, Abe T, Sohara N, Sato K, Takagi H, Mori M.
Ectopic varices rupture in the gastroduodenal anastomosis successfully treated with N-butyl-2-cyanoacrylate injection.
Acta Med Okayama. 61: 361-365, 2007.
Kaira K, Sunaga N, Yanagitani N, Hisada T, Ishizuka T, Mori M.
Pseudomesotheliomatous adenocarcinoma of the lung with synchronous gastric and esophageal cancer.
Australas Radiol. 51 Suppl: B265-B267, 2007.
Tosaka M, Sato N, Hirato J, Fujimaki H, Yamaguchi R, Kohga H, Hashimoto K, Yamada M, Mori M, Saito N, Yoshimoto Y.
Assessment of hemorrhage in pituitary macroadenoma by T2*-weighted gradient-echo MR imaging.
AJNR Am J Neuroradiol. 28: 2023-2029, 2007.
Kobayashi R, Okamura S, Ohno T, Saito H, Mori M, Ra C, Okayama Y.
Hyperexpression of FcgammaRI and Toll-like receptor 4 in the intestinal mast cells of Crohn's disease patients.
Clin Immunol. 125: 149-158, 2007.
Onozato Y, Kakizaki S, Ishihara H, Iizuka H, Sohara N, Okamura S, Mori M, Itoh H.
Endoscopic management of duodenal diverticular bleeding.
Gastrointest Endosc. 66: 1042-1049, 2007.
Takizawa D, Kakizaki S, Sohara N, Sato K, Takagi H, Arai H, Katakai K, Kojima A, Matsuzaki Y, Mori M.
Hepatocellular carcinoma with portal vein tumor thrombosis: clinical characteristics, prognosis, and patient survival analysis.
Dig Dis Sci. 52: 3290-3295, 2007.
Shimizu Y, Dobashi K, Mori M.
Exhaled breath marker in asthma patients with gastroesophageal reflux disease.
J Clin Biochem Nutr. 41: 147-153, 2007.
Shimoyama Y, Kusano M, Kawamura O, Zai H, Kuribayashi S, Higuchi T, Nagoshi A, Maeda M, Mori M.
High-viscosity liquid meal accelerates gastric emptying.
Neurogastroenterol Motil. 19: 879-86, 2007.
Kaira K, Oriuchi N, Otani Y, Shimizu K, Tanaka S, Imai H, Yanagitani N, Sunaga N, Hisada T, Ishizuka T, Dobashi K, Kanai Y, Endou H, Nakajima T, Endo K, Mori M.
Fluorine-18-alpha-methyltyrosine positron emission tomography for diagnosis and staging of lung cancer: a clinicopathologic study.
Clin Cancer Res. 13: 6369-6378, 2007.
Hashimoto K, Matsumoto S, Yamada M, Satoh T, Mori M.
Liver X receptor-alpha gene expression is positively regulated by thyroid hormone.
Endocrinology. 148: 4667-4675, 2007.
Tomizawa Y, Ishihara S, Iijima H, Imai H, Sato K, Yatomi M, Iwasaki Y, Yamada H, Kobayashi G, Ishida E, Inoue T, Aoki H, Watanabe S, Kawashima O, Mori M, Saito R.
A phase I dose escalation study of biweekly gemcitabine and carboplatin in completely resected stage IB-IIIA nonsmall cell lung cancer.
Am J Clin Oncol. 30: 498-502, 2007.
Yanagitani N, Tsuchiya S, Kaira K, Sunaga N, Tsuchiya Y, Sato K, Watanabe S, Nomura S, Sakai S, Saito R, Mori M.
Phase I study of biweekly paclitaxel and carboplatin for frail patients with advanced non-small cell lung cancer.
Am J Clin Oncol. 30: 487-491, 2007.
Hashizume H, Sato K, Takagi H, Hirokawa T, Kojima A, Sohara N, Kakizaki S, Mochida Y, Shimura T, Sunose Y, Ohwada S, Mori M.
Primary liver cancers with nonalcoholic steatohepatitis.
Eur J Gastroenterol Hepatol. 19: 827-834, 2007.
Kaira K, Dobashi K, Yanagitani N, Sunaga N, Shimizu Y, Hisada T, Ishizuka T, Nakajima T, Mori M.
Rapid growth of malignant pleural mesothelioma.
J Thorac Oncol. 2: 966-967, 2007.
Moki F, Kusano M, Mizuide M, Shimoyama Y, Kawamura O, Takagi H, Imai T, Mori M.
Association between reflux oesophagitis and features of the metabolic syndrome in Japan.
Aliment Pharmacol Ther. 26:1069-1075, 2007.
Ichikawa T, Oh-I S, Kaira K, Kakizaki S, Sato K, Takagi H, Mori M.
Education and imaging. Hepatobiliary and pancreatic: multifocal nodular hepatic steatosis associated with the metabolic syndrome.
J Gastroenterol Hepatol. 22: 1693, 2007.
Ishizuka T, Hisada T, Aoki H, Yanagitani N, Kaira K, Utsugi M, Shimizu Y, Sunaga N, Dobashi K, Mori M.
Gender and age risks for hoarseness and dysphonia with use of a dry powder fluticasone propionate inhaler in asthma.
Allergy Asthma Proc. 28: 550-556, 2007.
Kawamura O, Kusano M, Shimoyama Y, Horikoshi T, Sekiguchi T, Mori M.
Oral erythromycin accelerates impaired gastrointestinal motility after endoscopic mucosal resection.
Dig Dis Sci. 52: 2211-2220, 2007.
Koike Y, Hisada T, Utsugi M, Ishizuka T, Shimizu Y, Ono A, Murata Y, Hamuro J, Mori M, Dobashi K.
Glutathione redox regulates airway hyperresponsiveness and airway inflammation in mice.
Am J Respir Cell Mol Biol. 37: 322-329, 2007.
Yasuoka H, Masuo T, Hashimoto K, Sato K, Okada S, Kusano M, Oishi T, Yokoo H, Kojima M, Nakazato Y, Mori M.
Enteropathy-type T-cell lymphoma that was pathologically diagnosed as celiac disease.
Intern Med. 46: 1219-1224, 2007.
Kaira K, Shinomiya Y, Takahashi Y, Iida T, Yanagitani N, Sunaga N, Hisada T, Ishizuka T, Mori M.
Coinfection of invasive pulmonary aspergillosis and pneumocystis jiroveci pneumonia in a non-HIV patient.
Acta Med Okayama. 61: 235-238, 2007.
Sato K, Takagi H, Ishibashi A, Koyama Y, Mori M.
Small pancreatic lipoma: case report and literature review.
Hepatogastroenterology. 54: 1582-1584, 2007.
Kosone T, Takagi H, Horiguchi N, Ariyama Y, Otsuka T, Sohara N, Kakizaki S, Sato K, Mori M.
HGF ameliorates a high-fat diet-induced fatty liver.
Am J Physiol Gastrointest Liver Physiol. 293: G204-G210, 2007.
Onozato Y, Ishihara H, Iizuka H, Sohara N, Kakizaki S, Okamura S, Mori M.
A large flat adenoma located on the pylorus ring successfully treated by endoscopic submucosal dissection.
Dig Dis Sci. 52: 1738-1740, 2007.
Kusano M, Shimoyama Y, Kawamura O, Maeda M, Kuribayashi S, Nagoshi A, Zai H, Moki F, Horikoshi T, Toki M, Sugimoto S, Mori M.
Proton pump inhibitors improve acid-related dyspepsia in gastroesophageal reflux disease patients.
Dig Dis Sci. 52: 1673-1677, 2007.
Kaira K, Sunaga N, Tomizawa Y, Yanagitani N, Ishizuka T, Saito R, Nakajima T, Mori M.
Epigenetic inactivation of the RAS-effector gene RASSF2 in lung cancers.
Int J Oncol. 31: 169-173, 2007.
Sato K, Hayashi M, Utsugi M, Ishizuka T, Takagi H, Mori M.
Acute pancreatitis in a patient treated with micafungin.
Clin Ther. 29: 1468-1473, 2007.
Uehara Y, Mori M.
Hypolipidemia associated with hyperthyroidism.
Nippon Rinsho. 65 Suppl 7: 627-631, 2007.
Ariyama Y, Shimizu H, Satoh T, Tsuchiya T, Okada S, Oyadomari S, Mori M, Mori M.
Chop-deficient mice showed increased adiposity but no glucose intolerance.
Obesity (Silver Spring). 15: 1647-1656, 2007.
Sunaga N, Tomizawa Y, Yanagitani N, Iijima H, Kaira K, Shimizu K, Tanaka S, Suga T, Hisada T, Ishizuka T, Saito R, Dobashi K, Mori M.
Phase II prospective study of the efficacy of gefitinib for the treatment of stage III/IV non-small cell lung cancer with EGFR mutations, irrespective of previous chemotherapy.
Lung Cancer. 56: 383-389, 2007.
Horiguchi K, Yamada M, Umezawa R, Satoh T, Hashimoto K, Tosaka M, Yamada S, Mori M.
Somatostatin receptor subtypes mRNA in TSH-secreting pituitary adenomas: a case showing a dramatic reduction in tumor size during short octreotide treatment.
Endocr J. 54: 371-378, 2007.
Yanagitani N, Kaira K, Sunaga N, Naito Y, Koike Y, Ishihara S, Ishizuka T, Saito R, Mori M.
Serum amylase is a sensitive tumor marker for amylase-producing small cell lung cancer?
Int J Clin Oncol. 12: 231-233, 2007.
Shimizu Y, Dobashi K, Zhao JJ, Kawata T, Ono A, Yanagitani N, Kaira K, Utsugi M, Hisada T, Ishizuka T, Mori M.
Proton pump inhibitor improves breath marker in moderate asthma with gastroesophageal reflux disease.
Respiration. 74: 558-564, 2007.
Onozato Y, Kakizaki S, Ishihara H, Iizuka H, Sohara N, Okamura S, Mori M, Itoh H.
Endoscopic submucosal dissection for rectal tumors.
Endoscopy. 39: 423-427, 2007.
Kaira K, Shimizu Y, Sunaga N, Hisada T, Ishizuka T, Mori M.
Expectoration of bronchogenic tumour tissue.
Intern Med J. 37: 340-342, 2007.
Shimizu Y, Dobashi K, Hisada T, Ono A, Todokoro M, Iijima H, Utsugi M, Kakegawa S, Iizuka K, Ishizuka T, Morikawa A, Mori M.
Acute impact of volcanic ash on asthma symptoms and treatment.
Int J Immunopathol Pharmacol. 20(2 Suppl 2): 9-14, 2007.
Kaira K, Oriuchi N, Otani Y, Yanagitani N, Sunaga N, Hisada T, Ishizuka T, Endo K, Mori M.
Diagnostic usefulness of fluorine-18-alpha-methyltyrosine positron emission tomography in combination with 18F-fluorodeoxyglucose in sarcoidosis patients.
Chest. 131: 1019-1027, 2007.
Shimizu H, Inoue K, Mori M.
The leptin-dependent and -independent melanocortin signaling system: regulation of feeding and energy expenditure.
J Endocrinol. 193: 1-9, 2007.
Yamazaki Y, Kakizaki S, Horiguchi N, Sohara N, Sato K, Takagi H, Mori M, Negishi M.
The role of the nuclear receptor constitutive androstane receptor in the pathogenesis of non-alcoholic steatohepatitis.
Gut. 56: 565-574, 2007.
Yamazaki Y, Kakizaki S, Sohara N, Sato K, Takagi H, Arai H, Abe T, Katakai K, Kojima A, Matsuzaki Y, Mori M.
Hepatocellular carcinoma in young adults: the clinical characteristics, prognosis, and findings of a patient survival analysis.
Dig Dis Sci. 52: 1103-1107, 2007.
Okada S, Ohshima K, Uehara Y, Shimizu H, Hashimoto K, Yamada M, Mori M.
Synip phosphorylation is required for insulin-stimulated Glut4 translocation.
Biochem Biophys Res Commun. 356: 102-106, 2007.
Kakizaki S, Sohara N, Sato K, Suzuki H, Yanagisawa M, Nakajima H, Takagi H, Naganuma A, Otsuka T, Takahashi H, Hamada T, Mori M.
Preventive effects of vitamin K on recurrent disease in patients with hepatocellular carcinoma arising from hepatitis C viral infection.
J Gastroenterol Hepatol. 22: 518-522, 2007.
Kaira K, Sunaga N, Yanagitani N, Imai H, Utsugi M, Shimizu Y, Iijima H, Tomizawa Y, Hisada T, Ishizuka T, Saito R, Mori M.
A phase I dose-escalation study of S-1 plus carboplatin in patients with advanced non-small-cell lung cancer.
Anticancer Drugs. 18: 471-476, 2007.
Kosone T, Takagi H, Horiguchi N, Toyoda M, Sohara N, Kakizaki S, Sato K, Nishiyama U, Kuwaki T, Mori M.
Hepatocyte growth factor accelerates thrombopoiesis in transgenic mice.
Lab Invest. 87: 284-291, 2007.
Kaira K, Shimizu Y, Tsuchiya T, Mizuide M, Hisada T, Ishizuka T, Mori M.
Small cell carcinoma of the parotid gland.
Otolaryngol Head Neck Surg. 136: 330-331, 2007.
Shimizu H, Oh-I S, Okada S, Mori M.
Leptin resistance and obesity.
Endocr J. 54: 17-26, 2007.
Imai H, Tomizawa Y, Ishihara S, Sunaga N, Aoki H, Iijima H, Iwasaki Y, Watanabe S, Saito R, Mori M.
A case of pulmonary hypertrophic osteoarthropathy associated with primary lung cancer in a young adult successfully treated with gefitinib.
Nihon Kokyuki Gakkai Zasshi. 45: 189-193, 2007.
Kaira K, Yasuoka H, Ichikawa T, Oh-I S, Hisada T, Ishizuka T, Mori M.
Descending necrotizing mediastinitis after upper gastrointestinal endoscopy.
Endoscopy. 39 Suppl 1: E29, 2007.
Kaira K, Ishizuka T, Yanagitani N, Sunaga N, Hisada T, Mori M.
Effective combination chemotherapy of carboplatin and paclitaxel in the treatment of a recurrent small-cell lung cancer patient.
Gan To Kagaku Ryoho. 34: 225-227, 2007.
Imai H, Sunaga N, Kaira K, Ishihara S, Aoki H, Iijima H, Yanagitani N, Iwasaki Y, Tomizawa Y, Saito R, Mori M.
A case of multidrug-resistant non-small cell lung cancer responding to TS-1.
Gan To Kagaku Ryoho. 34: 221-224, 2007.
Kaira K, Ishizuka T, Yanagitani N, Sunaga N, Hisada T, Mori M.
Value of FDG positron emission tomography in monitoring the effects of therapy in progressive pulmonary sarcoidosis.
Clin Nucl Med. 32: 114-116, 2007.
Kaira K, Tsuchiya S, Sunaga N, Yanagitani N, Watanabe S, Imai H, Hisada T, Ishizuka T, Saito R, Mori M.
A phase I dose escalation study of weekly docetaxel and carboplatin in elderly patients with nonsmall cell lung cancer.
Am J Clin Oncol. 30: 51-56, 2007.
Kakizaki S, Yamazaki Y, Kosone T, Horiguchi N, Sohara N, Sato K, Takagi H, Yoshinari K, Mori M.
Gene expression profiles of drug-metabolizing enzymes and transporters with an overexpression of hepatocyte growth factor.
Liver Int. 27: 109-119, 2007.
英文原著 2006年
Arai H, Abe T, Takagi H, Mori M.
Efficacy of balloon-occluded retrograde transvenous obliteration, percutaneous transhepatic obliteration and combined techniques for the management of gastric fundal varices.
World J Gastroetenterol. 12: 3866-3873, 2006.
Hagiwara S, Takagi H, Kanda D, Sohara N, Kakizaki S, Katakai K, Yoshinaga T, Higuchi T, Nomoto K, Kuwano H, Mori M.
Hepatic adenomatosis associated with hormone replacement therapy and hemosiderosis: a case report.
World J Gastroenterol, 12: 652-655, 2006.
Hashida T, Yamada M, Hashimoto K, Satoh T, Okada S, Shibusawa N, Ishizuka T, Mori M.
Loss of consciousness and hypokalemia in an elderly man with a mutation of the thiazide sensitive Na-Cl cotransporter gene.
Endocr J. 53: 859-863, 2006.
Hashimoto K, Cohen RN, Yamada M, Markan KR, Monden T, Satoh T, Mori M, Wondisford FE.
Cross-talk between thyroid hormone receptor and liver X receptor regulatory pathways is revealed in a thyroid hormone resistance mouse model.
J Biol Chem. 281: 295-302, 2006.
Hashimoto K, Yamada M, Matsumoto S, Monden T, Satoh T, Mori M.
Mouse sterol response element binding protein-1c gene expression is negatively regulated by thyroid hormone.
Endocrinology. 147: 4292-4302, 2006.
Hisada T, Ishizuka T, Tomizawa Y, Iwasaki Y, Kawata T, Dobashi K, Mori M.
"Crazy-paving" appearance in systemic lupus erythematosus.
Intern Med. 45(1): 29-30, 2006.
Hisada T, Miyamae Y, Mizuide M, Shibusawa N, Iida T, Masuo T, Okada S, Sagawa T, Ishizuka T, Kusano M, Mori M.
Acute thrombocytopenia associated with preexisting ulcerative colitis successfully treated with colectomy.
Intern Med. 45(2): 87-91, 2006.
Iijima H, Tomizawa Y, Iwasaki Y, Sato K, Sunaga N, Dobashi K, Saito R, Nakajima T, Minna JD, Mori M.
Genetic and epigenetic inactivation of LTF gene at 3p21.3 in lung cancers.
Int J Cancer. 118(4): 797-801, 2006.
Ino K, Kusano M, Ohwada T, Kawamura O, Toki M, Sekiguchi T, Mori M.
Gastric Iongitudinal shortening may occur during gastric phase III activities in man.
J Gastroenterol Hepatol 21: 1839-1843, 2006.
Jun ZJ, Lei Y, Shimizu Y, Dobashi K, Mori M.
High seroprevalence of Helicobacter pylori in chronic bronchitis among Chinese population.
Tohoku J Exp Med. 208(4): 327-331, 2006.
Kaira K, Ishizuka T, Sohara N, Yanagitani N, Sunaga N, Tsuchiya T, Mori M.
Small cell carcinoma of the larynx in a long-term survivor of small-cell lung cancer.
J Clin Oncol. 24(18): 2961-2963, 2006.
Kaira K, Kawamura O, Mori M.
Intestinal Necrosis as a Result of Stanford Type B Aortic Dissection.
Clin Gastroenterol Hepatol. 4(9): 24, 2006.
Kaira K, Mori M.
Right thoracic stomach resulting from hiatal hernia.
Clin Gastroenterol Hepatol. 4(9): 28, 2006.
Kaira K, Takise A, Endou K, Yanagitani N, Sunaga N, Mori M.
A case of primary peritoneal serous papillary carcinoma initially presented by massive bilateral pleural effusions.
Eur J Gynaecol Oncol. 27(2): 197-199, 2006.
Kaira K, Takise A, Watanabe R, Mori M.
Fulminant hepatic failure resulting from small-cell lung cancer and dramatic response of chemotherapy.
World J Gastroenterol. 12(15): 2466-2468, 2006.
Kakizaki S, Takagi H, Yamazaki Y, Sohara N, Sato K, Nagamine T, Mori M.
Different outcomes of nosocomical infection with hepatitis C virus from the same origin.
World J Gastroenterol 12: 659-661, 2006.
Kasahara T, Tsunekawa K, Seki K, Mori M, Murakami M.
Regulation of iodothyronine deiodinase and roles of thyroid hormones in human coronary artery smooth muscle cells.
Atherosclerosis. 186: 207-214, 2006.
Kimura T, Tomura H, Mogi C, Kuwabara A, Damirin A, Ishizuka T, Sekiguchi A, Ishiwara M, Im DS, Sato K, Murakami M, Okajima F.
Role of scavenger receptor class B type I and sphingosine 1-phosphate receptors in high density lipoprotein-induced inhibition of adhesion molecule expression in endothelial cells.
J Biol Chem. 281(49): 37457-37467, 2006.
Kimura T, Tomura H, Mogi C, Kuwabara A, Ishiwara M, Shibasawa K, Sato K, Ohwada S, Im DS, Kurose H, Ishizuka T, Murakami M, Okajima F.
Sphingosine 1-phosphate receptors mediate stimulatory and inhibitory signalings for expression of adhesion molecules in endothelial cells.
Cell Signal. 18(6): 841-850, 2006.
Kohno T, Kunitoh H, Toyama K, Yamamoto S, Kuchiba A, Saito D, Yanagitani N, Ishihara S, Saito R, Yokota J.
Association of the OGG1-Ser326Cys polymorphism with lung adenocarcinoma risk.
Cancer Sci. 97(8): 724-728, 2006.
Kohno T, Sakiyama T, Kunitoh H, Goto K, Nishiwaki Y, Saito D, Hirose H, Eguchi T, Yanagitani N, Saito R, Sasaki-Matsumura R, Mimaki S, Toyama K, Yamamoto S, Kuchiba A, Sobue T, Ohta T, Ohki M, Yokota J.
Links Association of polymorphisms in the MTH1 gene with small cell lung carcinoma risk.
Carcinogenesis. 27(12): 2448-2454, 2006.
Koide H, Sato K, Fukusato T, Kashiwabara K, Sunaga N,Tsuchiya T, Morino S, Sohara N, Kakizaki S, Takagi H, Mori M.
Spontaneous regression of hepatic inflammatory pseudotumor with primary biliary cirrhosis: Case report and literature review.
World J Gastroenterol 12: 1645-1648, 2006.
Kosone T, Takagi H, Horiguchi N, Sohara N, Kakizaki S, Sato K, Yoneda M, Takeuchi T, Mori M.
Integrative roles of transforming growth factor-alpha in the cytoprotection mechanisms of gastric mucosal injury.
BMC Gastroenterology, 6: 22, 2006.
Machida T, Sato K, Kojima A, Takezawa J, Sohara N, Kakizaki S, Takagi H, Mori M.
Ruptured duodenal varices after endoscopic ligation of esophageal varices: An Autopsy Case.
Gastrointestinal Endoscopy. 63: 352-354, 2006.
Matsui M, Kojima A, Kakizaki S, Nagasaka K, Sohara N, Sato K, Takagi H, Maori M.
Ectopic varices in a right diaphragm that ruptured into the pleural cavity.
Acta Med Okayama, 60: 229-232, 2006.
Monden T, Nakajima Y, Hashida T, Ishii S, Tomaru T, Shibusawa N, Hashimoto K, Satoh T, Yamada M, Mori M, Kasai K.
Expression of thyroid hormone receptor isoforms down-regulated by thyroid hormone in human medulloblastoma cells.
Endocr J. 53: 181-187, 2006.
Nakajima H, Takagi H, Horiuchi N, Toyoda M, Kanda D, Otsuka T, Emoto Y, Emoto M, Mori M.
Lack of macrophage migration inhibitory factor protects mice against concanavalin A-induced liver injury.
Liver Int. 26: 346-351, 2006.
Nakajima Y, Takagi H, Sohara N, Sato K, Kakizaki S, Nomoto K, Suzuki H, Suehiro T, Shimura T, Asao T, Kuwano H, Mori M, Nishikura K.
A case of living-related liver transplantation for multiple liver metastases from rectal carcinoid tumor.
World J Gastroenterol 12: 1805-1809, 2006.
Nakano T, Arakawa K, Sakurai H, Hasegawa M, Yuasa K, Saito E, Takagi H, Nagamine T, Kusakabe T, Takada H, Nakazato K, Suzuki K, Kamiya T, Satoh T, Oikawa M, Sakai T.
Research of disease onset mechanism by determining the distribution of intracellular trace elements using an in-air micro-PIXE analyzing system.
Int J PIXE, 16: 69-76, 2006.
Oh-I S, Shimizu H, Satoh T, Okada S, Adachi S, Inoue K, Eguchi H, Yamamoto M, Imaki T, Hashimoto K, Tsuchiya T, Monden T, Horiguchi K, Yamada M, Mori M.
Identification of nesfatin-1 as a satiety molecule in the hypothalamus.
Nature. 443: 709-712, 2006.
Onozato Y, Ishihara H, Iizuka H, Sohara N, Kakizaki S, Okamura S, and Mori M.
Endoscopic submucosal dissection (ESD) for early gastric cancers and large flat adenomas.
Endoscopy. 38: 980-986, 2006
Sato K, Takagi H, Kakizaki S, Sohara N, Mori M.
Adefovir dipivoxil monotherapy is a sufficiently effective treatment modality for Japanese patients with lamivudine-resistant chronic hepatitis B.
J Gastroenterol. 41: 283-285, 2006.
Sato K, Tomizawa Y, Iijima H, Saito R, Ishizuka T, Nakajima T, Mori M.
Epigenetic inactivation of the RUNX3 gene in lung cancer.
Oncol Rep. 15(1): 129-135, 2006.
Sato K, Yamada E, Uehara Y, Takagi H, Mori M.
Possible role for human leukocyte antigen haplotype in rofecoxib-associated acute pancreatitis and cholestatic hepatitis.
Clin Pharmacol Ther. 80(5): 554-555, 2006.
Sato M, Vaughan MB, Girard L, Peyton M, Lee W, Shames DS, Ramirez RD, Sunaga N, Gazdar AF, Shay JW, Minna JD.
Multiple oncogenic changes (K-RAS(V12), p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells.
Cancer Res. 66: 2116-2128, 2006.
Sekiguchi T, Nagamine T, Takagi H, Mori M.
Autoimmune thrombocytopenia in response to splenectomy in cirrhotic patients with accompanying hepatitis C.
World J Gastroenterol 12: 1265-1269, 2006.
Sekiguchi T, Nagamine T, Takagi H, Mori M.
Reduction of virus burden induced splenectomy in patients with liver cirrhosis related to hepatitis C virus infection.
World J Gastroenterol. 12: 2089-2094, 2006.
Shimizu H, Oh-I S, Tsuchiya T, Ohtani KI, Okada S, Mori M.
Pioglitazone increases circulating adiponectin levels and subsequently reduces TNF-alpha levels in Type 2 diabetic patients: a randomized study.
Diabet Med. 23: 253-257, 2006.
Shimizu Y, Dobashi K, Kobayashi S, Ohki I, Tokushima M, Kusano M, Kawamura O, Shimoyama S, Utsugi M, Sunaga N, Ishizuka T, Mori M.
A Proton Pump Inhibitor, Lansoprazole, Ameliorates Asthma Symtoms in Asthmatic Patients with Gastroesophageal Reflux disease.
Tohoku J. Exp. Med. 209: 181-189, 2006.
Shimizu Y, Dobashi K, Kobayashi S, Ohki I, Tokushima M, Kusano M, Kawamura O, Shimoyama Y, Utsugi M, Mori M.
High Prevalence of Gastroesophageal Reflux Disease with Minimal Mucosal Changes in Asthmatic Patients.
Tohoku J. Exp. Med. 209: 329-336, 2006.
Shimizu Y, Dobashi K, Mita Y, Endou K, Moriya S, Osano K, Koike Y, Higuchi S, Yabe S, Utsugi M, Ishizuka T, Hisada T, Nakazawa T, Mori M.
DNA microarray genotyping of N-acetyltransferase 2 polymorphism using carbodiimide as the linker for assessment of isoniazid hepatotoxicity.
Tuberculosis. 86(5): 374-381, 2006.
Shimizu Y, Kuwabara H, Ono A, Higuchi S, Hisada T, Dobashi K, Utsugi M, Mita Y, Mori M.
Intracellular Th1/Th2 balance of pulmonary CD4(+) T cells in patients with active interstitial pneumonia evaluated by serum KL-6.
Immunopharmacol Immunotoxicol. 28(2): 295-304, 2006.
Sohara N, Takagi H, Kakizaki S, Sato K and Mori M.
The use of partial splenic artery embolization made it possible to administer interferon and ribavirin in a liver transplant patient with fibrosing cholestatic hepatitis C complicated with thrombocytopenia.
Transplant Int 19: 255-257, 2006.
Sun R, Park O, Horiguchi N, Kurkarni S, Jeong WI, Sun HY, Radaeva S, Gao B.
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当教室は初代七条小次郎教授(昭和19年?昭和47年)、2代目小林節雄教授(昭和47年?平成3年)、3代目森教授(平成3年8月?)に継承され、これまで約60年の歴史があります。この間多数の教室員が切磋琢磨して教室を盛り上げて来ており、当科の教室員から多くの教授や国公立病院長を輩出し、また医師会長として地域医療の面で活躍している同門生も数多くいます。病態制御内科学(第一内科)の伝統は「多様性の展開と人材育成」であり、これは現在更に着実に推進されています。
社会貢献としては、特に群大医師会等をとうして一般医師を対象とした学術講演会を活発に行っていることと、各スタッフは自己の所属する学会や研究会で活発な臨床研究報告を行っていること、またそれらの研究成果の開発を地元研究所等と共に製品化すべく共同研究を推進していることなどです。